5.Identification and masking of repeat elements
Repeat identification Usually the first step for the genome annotation is the repeat identification and masking. With the term of "repeat" we mean different type of sequences like: Low complexity sequences as homopolymeric runs of nucleotides, transposable elements, viruses, long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs).
The masking of a genome consists of two steps: 1) The built of the repeats data base and 2) the masking by using the data base.
For the construction of the repeat database we are using the RepeatModeler. RepeatModeler is a de-novo repeat family identification and modeling package.